NGS: Is long-read sequencing better or more accurate than short read sequencing?
Oxford Nanopore Technologies (ONT) is a company that produces devices and reagents for DNA and RNA sequencing using a method called nanopore sequencing. One of the main advantages of ONT's sequencing technology is that it can produce long reads, which are contiguous sequences of DNA that are several thousand base pairs in length. In general, long reads can be more accurate than shorter reads because they provide more context and more information about the sequence.
ONT's technology has been shown to produce high-quality, long reads that are generally considered to be accurate. However, the accuracy of any sequencing method depends on a number of factors, including the quality of the sample, the efficiency of the sequencing reaction, and the specific platform and protocols used. In some cases, other sequencing technologies, such as Illumina's short-read sequencing, may be more accurate for certain applications.
It is important to note that there is no single "best" sequencing technology that is universally superior in all situations. The choice of technology will depend on the specific needs and goals of the experiment. It is always advisable to carefully consider the pros and cons of different sequencing technologies and to select the one that is most appropriate for the specific application at hand.